The Big Buffalo Valley Historic District, also known as the Boxley Valley Historic District, is notable as a cultural landscape in Buffalo National River. It comprises the Boxley Valley in northern Arkansas, near the town of Boxley. The valley includes a number of family-operated farms, primarily dating between 1870 and 1930. The farms are situated on either side of the road that parallels the river, Arkansas Highway 43. Many of these farms are still operated by the descendants of the original homesteaders. However, of fifty residences in the valley, thirty were vacant in 1987, at the time of historic designation.